More than 50 people are in critical condition after receiving a routine dose of the highly contagious coronavirus vaccine in Louisiana, according to the state Department of Health.
More than 40 people have been hospitalized after being treated for coronaviruses in Louisiana.
At least eight people have died and another 10 have been treated for COVID.
The state of Louisiana is home to about 830,000 people, most of whom live in the city of New Orleans, which has seen an outbreak of coronavides in recent years.
Centers for Disease Control and Prevention (CDC) on Wednesday announced that it had added six more states to its list of states in the process of reporting an unprecedented spike in COVID cases in recent weeks.
On Tuesday, the CDC said that California had reported the most cases of the COVID virus, and that nine people had died of COVI.
The new state of New York reported the highest number of coronovirus cases since September, when more than 9,000 cases were reported.
California also reported the largest number of new coronavirets in a single day, with more than 5,000.
New York also had the highest death toll for COVI, with two people in New York City and one person in the Bronx dying.